LC/MS/MS

Kinomica’s LC/MS/MS Quantitative Phosphoproteomics methodology has been developed on cutting edge instrumentation. Initially developed on the LTQ-Orbitrap platform in 2008, it has been continually improved and enhanced as the Mass Spectrometry instruments have evolved to higher and faster performance levels.

the ultimate 3000 lc/ms/ms mass spectrometer lc/ms/ms ultimate 3000 mass spectrometer
close up of the lens part of the lc/ms/ms mass spectrometer

The K-Scan platform takes the LC/MS/MS raw data as its input; the minimum performance standard is validated on the Q-Exactive Plus. Data can be used from other types of Mass Spectrometer, meeting an equivalent-or-better level of performance.

Reliable and Reproducible data, across large batches, is critical to K-Scan’s success. To ensure liquid handling is accurate, Kinomica employ the Bravo AssayMAP for the phosphoenrichment part of the method.

sceintist examining data on a large computer screen

The Solution: KScan®

KScan®: A next generation biomarker and molecular diagnostics platform

What is KScan®?

A patented database of kinase substrate relationships

Patented algorithms to determine which kinases are enriched

Kinase Activity Leader Board - K-Score

Patented Method for systematic identification of regulatory protein kinases (K-Score)

Significance of KScan®

KScan lc/ms/ms diagram shwoing drug efficacy against kinase activities
close up image of the lc/ms/ms mass spectrometer

LC/MS/MS Publication

Take a look at our library of publications and presentations that cover the topic of our LC/MS/MS technology in more detail.

Technologies

Find out more about Kinomica’s powerful suite of advanced proprietary bioinformatics and phosphoproteomics analytical methods

LC/MS/MS mass spectrometer KScan phosphoproteomics platform
scientist in a white coat looking at a laptop male scientist wearing a white coat looking at a laptop screen

Kinomica News

Learn more about Kinomica, our team and our technology through our in-depth blog content. We’ll also let you know what events we are attending as well. 

Talk to our Experts

To find out more about the technology behind Kinomica’s advanced bioinformatics and phosphoproteomics analytical methods, talk to our experts.

Contact Us

If you have any questions or need any further information, then please contact the Kinomica team – we are more than happy to help.

“Our technology and analysis capabilities will mean than patients can be matched to the correct drugs reducing time spent on ineffective medicines and increasing lifespans and quality of life”

Jane Theaker, Kinomica CEO